Overview
Addison's disease, also known as primary adrenal insufficiency, is a rare disorder that occurs when the adrenal glands do not produce enough hormones, including cortisol and aldosterone. These hormones play important roles in regulating metabolism, blood pressure, and other bodily functions. Symptoms of Addison's disease can include fatigue, muscle weakness, weight loss, low blood pressure, darkening of the skin, and salt cravings. The condition can be caused by autoimmune disorders, infections, cancer, and certain medications. Diagnosis typically involves blood tests, imaging tests, and sometimes a stimulation test to measure hormone levels. Treatment involves hormone replacement therapy, which involves taking cortisol and aldosterone supplements. Without treatment, Addison's disease can be life-threatening. However, with proper treatment and management, most people with the condition can lead normal lives. Regular monitoring and adjustment of hormone replacement therapy may be necessary to ensure optimal health.