Angioedema

Angioedema is a medical condition characterized by swelling in the deeper layers of the skin and tissues beneath the skin. This swelling usually affects the face, lips, tongue, throat, and sometimes the hands and feet. Angioedema can be hereditary or acquired and can be triggered by various factors such as allergic reactions, medications, infections, and autoimmune diseases. Hereditary angioedema (HAE) is a rare genetic disorder that causes recurrent episodes of swelling, abdominal pain, and difficulty breathing. Acquired angioedema (AAE) can be caused by autoimmune disorders, lymphoproliferative disorders, or use of certain medications like ACE inhibitors. Treatment for angioedema depends on the underlying cause and severity of symptoms. Mild cases may not require any treatment, but severe cases may require medications such as antihistamines, corticosteroids, or epinephrine. For hereditary angioedema, specific medications like C1 inhibitor replacement therapy, bradykinin B2 receptor antagonists or kallikrein inhibitors may be used. It is essential to seek prompt medical attention if you suspect angioedema, especially if you experience difficulty breathing, swelling of the tongue or throat, or severe abdominal pain.